|
Celiac Disease
|
0.500 |
GeneticVariation
|
disease |
GWASDB |
A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21.
|
17558408 |
2007 |
|
Celiac Disease
|
0.500 |
GeneticVariation
|
disease |
GWASDB |
Multiple common variants for celiac disease influencing immune gene expression.
|
20190752 |
2010 |
|
Celiac Disease
|
0.500 |
Biomarker
|
disease |
HPO |
|
|
|
|
Celiac Disease
|
0.500 |
GeneticVariation
|
disease |
LHGDN |
Conspicuous frequencies of the alleles associated with susceptibility to CD were observed (DQA1*0501: 0.592, DQB1*0201: 0.471).
|
15120190 |
2004 |
|
Celiac Disease
|
0.500 |
Biomarker
|
disease |
LHGDN |
HLA-DQ determines the response to exogenous wheat proteins: a model of gluten sensitivity in transgenic knockout mice.
|
12421937 |
2002 |
|
Celiac Disease
|
0.500 |
GeneticVariation
|
disease |
LHGDN |
HLA DQA1*0501 and DQB1*02 in Cuban celiac patients.
|
16916661 |
2006 |
|
Celiac Disease
|
0.500 |
GeneticVariation
|
disease |
LHGDN |
The HLA DQA1 DQB1 high-risk genotypes associated with celiac disease are similar in these Bedouin families with CD to what is observed in Northern and Southern Europeans.
|
12039527 |
2002 |
|
Celiac Disease
|
0.500 |
Biomarker
|
disease |
LHGDN |
HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac disease.
|
16878175 |
2006 |
|
Celiac Disease
|
0.500 |
Biomarker
|
disease |
LHGDN |
HLA-DQ and susceptibility to celiac disease: evidence for gender differences and parent-of-origin effects.
|
18177450 |
2008 |
|
Celiac Disease
|
0.500 |
GeneticVariation
|
disease |
GWASCAT |
A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21.
|
17558408 |
2007 |
|
Celiac Disease
|
0.500 |
GeneticVariation
|
disease |
GWASCAT |
Multiple common variants for celiac disease influencing immune gene expression.
|
20190752 |
2010 |
|
Celiac Disease
|
0.500 |
Biomarker
|
disease |
CTD_human |
|
|
|
|
Celiac Disease
|
0.500 |
Biomarker
|
disease |
BEFREE |
HLA types in celiac disease patients not carrying the DQA1*05-DQB1*02 (DQ2) heterodimer: results from the European Genetics Cluster on Celiac Disease.
|
12651074 |
2003 |
|
Celiac Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Conspicuous frequencies of the alleles associated with susceptibility to CD were observed (DQA1*0501: 0.592, DQB1*0201: 0.471).
|
15120190 |
2004 |
|
Celiac Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
HLA in coeliac disease families: a novel test of risk modification by the 'other' haplotype when at least one DQA1*05-DQB1*02 haplotype is carried.
|
12392509 |
2002 |
|
Celiac Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Celiac disease (CD) is associated with tissue transglutaminase autoantibodies (tTGAs) in individuals carrying the human leukocyte antigen (HLA) risk haplotypes DQA1*05:01-DQB1*02:01 (DQ2) and/or DQA1*03:01-DQB1*03:02 (DQ8).
|
26301618 |
2016 |
|
Celiac Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
HLA DQA1*05 and DQB1*02 alleles encoding the DQ2.5 molecule and HLA DQA1*03 and DQB1*03 alleles encoding DQ8 molecules are strongly associated with celiac disease (CD) and type 1 diabetes (T1D), two common autoimmune diseases (AD).
|
31331105 |
2019 |
|
Celiac Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
We like to suggest that the haplotype HLA-DQA1*03-DQB1*03:03 (HLA-DQ9.3), which is common in Chinese, is a new susceptibility factor for CD in China.
|
26496305 |
2015 |
|
Celiac Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Four modified sequence specific primers (SSP) pairs were designed for the selective amplification of coeliac disease associated alleles (DQA1*05, DQB1*02, DQB1*03:02 alleles), and human growth hormone (positive control).
|
26043316 |
2015 |
|
Celiac Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
The prevalence of the HLA-DQA1 and DQB1 alleles in 55 Turkish children with celiac disease and 50 control subjects was investigated by using an allele-specific DNA-based polymerase chain reaction-sequence-specific primer (PCR-SSP) method.
|
11556984 |
2001 |
|
Celiac Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
We retrospectively reviewed the medical records of 127 consecutive cases of adult-onset celiac disease evaluated at a single United States center to determine the distribution of the associated human leukocyte antigen DQA1 and DQB1 alleles.
|
21292306 |
2011 |
|
Celiac Disease
|
0.500 |
Biomarker
|
disease |
BEFREE |
The presence of the DQ2 (DQA1*0501/DQB1*02) heterodimer is strongly associated with celiac disease in the population studied by the authors.
|
14581805 |
2003 |
|
Celiac Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
In contrast, the DQA1*0501 allele did not have a significant association with the severity of CD.
|
16484124 |
2006 |
|
Celiac Disease
|
0.500 |
Biomarker
|
disease |
BEFREE |
Because of rarely reported cases of CD/rhabdomyolysis, anti-tissue transglutaminase (tTG) antibodies were measured and found positive (IgA 34 U/mL, unv <9).HLA typing was DQA1 05:02, DQB1 03:02.
|
28606713 |
2018 |
|
Celiac Disease
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Genetic susceptibility of celiac disease is primarily associated with a particular combination of and HLA-DQA1/DQB1 gene; however, this does not fully account for the genetic predisposition.
|
8253354 |
1993 |